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Drug Interactions between Flumezide and iodixanol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

bendroflumethiazide rauwolfia serpentina

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina) and Flumezide (bendroflumethiazide / rauwolfia serpentina)

Before taking bendroflumethiazide, tell your doctor if you also use rauwolfia serpentina. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take rauwolfia serpentina at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

bendroflumethiazide iodixanol

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina) and iodixanol

Before you undergo any imaging procedure where iodixanol may be given by injection, let your doctor know if you are currently being treated with bendroflumethiazide. Injection of iodixanol can sometimes cause kidney problems, and the risk may be increased if you are also using bendroflumethiazide. The interaction may be more likely if you have preexisting kidney disease, congestive heart failure, or diabetes; or if you are elderly, dehydrated, or taking other medications that can affect the kidney. Depending on your health situation, your doctor may want you to stop using bendroflumethiazide for a certain length of time before and after the procedure. You may also be asked to increase your fluid intake the day before the procedure, or you may be given intravenous fluids before, during, and after the procedure. Since iodixanol contains iodine, also let your doctor know if you have had a previous reaction to iodine or iodine-containing products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

bendroflumethiazide food

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina)

Bendroflumethiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

rauwolfia serpentina food

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina)

Rauwolfia serpentina and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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