Drug Interactions

Drug interactions between Florinef and midodrine

Results for the following 2 drugs:

Florinef (fludrocortisone)
midodrine

Interactions between your selected drugs

fludrocortisone ⇔ midodrine

Applies to: Florinef (fludrocortisone) and midodrine

MONITOR: Although midodrine is often used with fludrocortisone (with or without salt supplementation) for the treatment of orthostatic hypotension, this combination may lead to excessive increases in blood pressure and intraocular pressure. Glaucoma may be aggravated in some patients.

MANAGEMENT: Caution is advised, especially in patients with ocular diseases. Blood pressure and intraocular pressure should be monitored during concomitant use. Prior to initiating treatment with midodrine it may be prudent to decrease the dose of fludrocortisone or decrease the patient's salt intake.

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