Drug interactions between eptifibatide and Plavix
| Results for the following 2 drugs: |
|---|
| eptifibatide |
| Plavix (clopidogrel) |
Interactions between your selected drugs
clopidogrel ↔ eptifibatide
Applies to:Plavix (clopidogrel) and eptifibatide
GENERALLY AVOID: The combination of glycoprotein IIb/IIIa inhibitors and other drugs that inhibit platelet aggregation significantly increase the risk of bleeding, especially from arterial puncture sites. The mechanism is synergistic pharmacologic effects.
MANAGEMENT: Extraordinary precautions are recommended if these drugs must be used together, including monitoring platelet counts and hemoglobin concentrations. In addition, invasive procedures, such as urinary catheterization, nasogastric or nasotracheal intubation, and even venous punctures should be avoided or minimized. Non-compressible venous access sites, such as jugular or subclavian sites, should be avoided.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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