Drug Interactions between diroximel fumarate and Propoxyphene Compound 65
This report displays the potential drug interactions for the following 2 drugs:
- diroximel fumarate
- Propoxyphene Compound 65 (aspirin/caffeine/propoxyphene)
Interactions between your drugs
aspirin diroximel fumarate
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene) and diroximel fumarate
The use of diroximel fumarate in combination with higher doses of aspirin, such as those used to relieve pain and inflammation, may increase the potential for kidney damage. Let your doctor know if you experience any signs or symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and/or irregular heart rhythm. You can also speak with your healthcare provider to see if an alternative pain reliever, such as acetaminophen, might be an option for you.
Lower doses of non-enteric coated aspirin (up to 325 mg) are sometimes taken about 30 minutes prior to diroximel fumarate to help reduce the occurrence and severity of flushing. This combination has not been evaluated for longer than 4 weeks. Let your doctor know if you experience any side effects that are particularly bothersome or do not improve during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin caffeine
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene) and Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Information for this minor interaction is available on the professional version.
Drug and food interactions
propoxyphene food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Do not use alcohol or medications that contain alcohol while you are receiving treatment with propoxyphene. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. Do not use more than the recommended dose of propoxyphene, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
diroximel fumarate food
Applies to: diroximel fumarate
Taking diroximel fumarate with high-fat, high-calorie meals or snacks may reduce the levels of active medication in the blood, which may make the medication less effective in treating your condition. Food may help improve the tolerability of diroximel fumarate if you are experiencing flushing or gastrointestinal side effects from the medication; however, meals or snacks should contain no more than 700 calories and no more than 30 grams of fat. In addition, you should avoid or limit the use of alcohol while being treated with diroximel fumarate. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
caffeine food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Information for this minor interaction is available on the professional version.
aspirin food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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