Drug Interactions between Demulen 1/35 and pirfenidone
This report displays the potential drug interactions for the following 2 drugs:
- Demulen 1/35 (ethinyl estradiol/ethynodiol)
- pirfenidone
Interactions between your drugs
ethinyl estradiol pirfenidone
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol) and pirfenidone
Ethinyl estradiol may increase the blood levels of pirfenidone. In some cases, this can increase the risk and/or severity of side effects such as liver problems, sensitivity to sunlight, rash, dizziness, diarrhea, nausea, vomiting, and upset stomach. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
pirfenidone food
Applies to: pirfenidone
Pirfenidone should be taken with food to help reduce dizziness and gastrointestinal side effects such as diarrhea, nausea, vomiting, and upset stomach. Avoid smoking during treatment, as cigarette smoking can reduce the blood levels and effects of pirfenidone. If you are a smoker, you should try to quit smoking before starting treatment. Talk to your doctor or pharmacist if you have any questions or concerns, or need help in finding a smoking cessation program. You should also avoid consuming grapefruit or grapefruit juice while taking pirfenidone, as it may increase blood levels of the medication and lead to more side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ethinyl estradiol food
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)
Information for this minor interaction is available on the professional version.
ethynodiol food
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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