Drug Interactions between Demulen 1/35 and entrectinib
This report displays the potential drug interactions for the following 2 drugs:
- Demulen 1/35 (ethinyl estradiol/ethynodiol)
- entrectinib
Interactions between your drugs
ethinyl estradiol entrectinib
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol) and entrectinib
Entrectinib may reduce the blood levels and effectiveness of ethinyl estradiol, which may make it less reliable as a form of birth control. Alternative or additional methods of birth control such as condoms should be used during treatment with entrectinib and for up to 5 weeks after stopping treatment to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional for help in selecting an effective method of birth control that is best for you. Men receiving entrectinib should also use a condom during the treatment period and for 3 months after stopping treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ethynodiol entrectinib
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol) and entrectinib
Entrectinib may reduce the blood levels and effectiveness of ethynodiol, which may make it less reliable as a form of birth control. Alternative or additional methods of birth control such as condoms should be used during treatment with entrectinib and for up to 5 weeks after stopping treatment to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional for help in selecting an effective method of birth control that is best for you. Men receiving entrectinib should also use a condom during the treatment period and for 3 months after stopping treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
entrectinib food
Applies to: entrectinib
Do not consume grapefruit, grapefruit juice, or Seville oranges during treatment with entrectinib. Doing so can significantly increase the blood levels of entrectinib and increase the risk and/or severity of side effects such as dizziness; confusion; hallucinations; problems with concentration, attention, thinking, and memory; mood changes; insomnia; drowsiness; liver problems; increased uric acid levels in the blood (hyperuricemia); congestive heart failure; fluid retention and swelling; changes in electrical activity of the heart (a condition known as QT prolongation, which may lead to irregular heart rhythm that can be life-threatening); vision problems; and low red or white blood cell counts. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ethinyl estradiol food
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)
Information for this minor interaction is available on the professional version.
ethynodiol food
Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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