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Drug Interactions between deflazacort and sodium iodide-i-131

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

sodium iodide I-131 deflazacort

Applies to: sodium iodide-i-131 and deflazacort

Deflazacort may affect the diagnostic results of sodium iodide I-131. Talk to your doctor before you are scheduled for testing to find out if and for how long you should stop using deflazacort so that it does not interfere with sodium iodide I-131 test results. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

sodium iodide I-131 food

Applies to: sodium iodide-i-131

Iodine may interfere with the uptake of sodium iodide I-131 by the thyroid . A diet low in iodine and iodinated salt is recommended before starting therapy with sodium iodide I-131.

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Moderate

deflazacort food

Applies to: deflazacort

Do not take deflazacort with grapefruit juice. Grapefruit juice may increase the blood levels of the active component of deflazacort. This may increase the risk and/or severity of side effects such as swelling, weight gain, electrolyte abnormalities, high blood pressure, high blood glucose, muscle weakness, depression, mood swings, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, glaucoma, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Other side effects that may occur include decreased ability to fight infections, increased risk of developing infections, and inadequate response to stress such as infection, surgery, trauma, or a severe asthma attack. Children may experience a reduced growth rate during chronic use. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

sodium iodide I-131 food

Applies to: sodium iodide-i-131

Multivitamin with minerals may affect the diagnostic results of sodium iodide I-131. Talk to your doctor before you are scheduled for testing to find out if and for how long you should stop using multivitamin with minerals so that it does not interfere with sodium iodide I-131 test results. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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