Drug interactions between Cymbalta and Quinaretic
| Results for the following 2 drugs: |
|---|
| Cymbalta (duloxetine) |
| Quinaretic (hydrochlorothiazide/quinapril) |
Interactions between your selected drugs
hydrochlorothiazide ↔ duloxetine
Applies to:Quinaretic (hydrochlorothiazide/quinapril) and Cymbalta (duloxetine)
Talk to your doctor before using DULoxetine together with hydrochlorothiazide. DULoxetine may occasionally cause your blood sodium levels to get too low, and using it with hydrochlorothiazide can increase that risk. Let your doctor know if you experience headache, difficulty concentrating, memory impairment, confusion, weakness, or unsteadiness while using these medications, as they may be symptoms of an inadequate blood sodium level. More severe cases may include hallucination, fainting, seizure, coma, and even death. DULoxetine can also affect your blood pressure and heart rate. You may need a dose adjustment or more frequent monitoring of your blood pressure and pulse to safely use both medications. You should avoid rising abruptly from a sitting or lying position while taking these medications, especially at the beginning of treatment or after an increase in dose. Call your doctor if you experience dizziness, lightheadedness, fainting, or a rapid heart beat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Switch to professional interaction data
quinapril ↔ duloxetine
Applies to:Quinaretic (hydrochlorothiazide/quinapril) and Cymbalta (duloxetine)
Quinapril and DULoxetine may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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