Drug Interactions between Combigan and Jaypirca
This report displays the potential drug interactions for the following 2 drugs:
- Combigan (brimonidine/timolol ophthalmic)
- Jaypirca (pirtobrutinib)
Interactions between your drugs
timolol ophthalmic brimonidine ophthalmic
Applies to: Combigan (brimonidine / timolol ophthalmic) and Combigan (brimonidine / timolol ophthalmic)
After using brimonidine ophthalmic, some of the medication may be absorbed into the bloodstream and occasionally produce cardiovascular side effects such as decreases in blood pressure and heart rate. Combining it with timolol ophthalmic or other medications that can also have these effects may increase the risk. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart beat. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
pirtobrutinib food
Applies to: Jaypirca (pirtobrutinib)
Consumption of grapefruit, grapefruit juice, and supplements that contain grapefruit should be avoided during treatment with pirtobrutinib as they may increase the blood levels of pirtobrutinib. This may increase the risk of side effects such as infection, bruising, bleeding, fatigue, muscle pain, diarrhea, swelling, and difficulty breathing. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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