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Drug Interactions between cholera vaccine and Rethymic

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

cholera vaccine allogeneic processed thymus tissue

Applies to: cholera vaccine and Rethymic (allogeneic processed thymus tissue)

Patients that have been treated with allogeneic processed thymus tissue should let their doctor know before receiving cholera vaccine. Allogeneic processed thymus tissue is intended to help the body develop a part of the immune system called T cells, which are important to help the body fight infections and can help vaccines work to protect the body against certain diseases. Depending on the length of time since they have been treated with allogeneic processed thymus tissue, their body may not have had enough time to develop this part of the immune system, which may lead to a reduced response to cholera vaccine. In some situations, their doctor may want to delay vaccination with cholera vaccine until the patient's immune system is improved. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

cholera vaccine food

Applies to: cholera vaccine

Consumer information for this interaction is not currently available.

ADJUST DOSING INTERVAL: Coadministration of oral cholera vaccine with food or an oral beverage may impair its efficacy. The formulations of both the inactivated and live, attenuated oral cholera vaccines (Dukoral and Vaxchora, respectively) are acid-labile, and must be administered with a buffer. According to the manufacturer, eating and drinking may interfere with the protective effect of the buffer. However, clinical data are not available.

MANAGEMENT: It is recommended that patients avoid eating or drinking for 60 minutes before and after administration of either Dukoral or Vaxchora oral cholera vaccines.

References

  1. (2023) "Product Information. Vaxchora (cholera vaccine, live)." Patientric Ltd
  2. (2022) "Product Information. Dukoral (vibrio cholerae vaccine)." Valneva Sweden AB
  3. (2023) "Product Information. Dukoral (cholera vaccine)." Valneva UK Ltd
  4. (2024) "Product Information. Vaxchora (cholera vaccine, live)." Emergent Travel Health, Inc
View all 4 references

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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