Drug interactions between Calcium 600 D and carbidopa/entacapone/levodopa
| Results for the following 2 drugs: |
|---|
| Calcium 600 D (calcium/vitamin d) |
| carbidopa/entacapone/levodopa |
Interactions between your selected drugs
levodopa ↔ calcium carbonate
Applies to:carbidopa/entacapone/levodopa and Calcium 600 D (calcium/vitamin d)
Antacids and some oral aluminum, calcium, or magnesium containing preparations may increase the absorption of levodopa. The mechanisms may be related to increased gastric pH and/or decreased gastric emptying time, resulting in less gastric degradation of levodopa and more levodopa absorption from the small intestine. This effect may be beneficial in some patients, but also difficult to predict and monitor. For most patients, this interaction is not clinically significant and no specific intervention would be required. Dosing intervals could be spaced by at least 2 hours if it is preferred to avoid this interaction.
See also...
- Carbidopa/entacapone/levodopa Drug Interactions
- carbidopa, entacapone, and levodopa General Consumer Information
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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