Drug interactions between Byetta and insulin detemir
| Results for the following 2 drugs: |
|---|
| Byetta (exenatide) |
| insulin detemir |
Interactions between your selected drugs
insulin detemir ↔ exenatide
Applies to:insulin detemir and Byetta (exenatide)
GENERALLY AVOID: The concomitant use of glucagon-like peptide-1 (GLP-1) receptor agonists and insulin has not been studied. GLP-1 receptor agonists lower blood glucose by stimulating insulin secretion and lowering glucagon secretion. The impact of these actions during insulin administration is unknown.
MANAGEMENT: The use of GLP-1 receptor agonists such as exenatide or liraglutide in combination with insulin has not been studied and cannot be recommended. If concomitant use is required, the dosage of insulin should be evaluated carefully. In patients at increased risk of hypoglycemia, consider reducing the dosage of insulin.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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