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Drug Interactions between burosumab and Visicol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

sodium phosphate burosumab

Applies to: Visicol (sodium biphosphate / sodium phosphate) and burosumab

Using burosumab together with sodium phosphate is not recommended. Combining these medications may cause excessive elevations in phosphorus and vitamin D levels in the blood, which may lead to increased risk of kidney stones. Over time, you may also have bone and muscle problems as well as increased risk of heart attacks and strokes if the blood levels remain high. Most products containing phosphates and greater than nutritional allowances of vitamin D should generally be discontinued for one week before starting treatment with burosumab. Talk to your doctor if you have any questions or concerns. During treatment, phosphorus blood levels should be closely monitored, which will allow your doctor to determine when a dose adjustment or an interruption in treatment may be required. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Major

sodium biphosphate burosumab

Applies to: Visicol (sodium biphosphate / sodium phosphate) and burosumab

Using burosumab together with sodium biphosphate is not recommended. Combining these medications may cause excessive elevations in phosphorus and vitamin D levels in the blood, which may lead to increased risk of kidney stones. Over time, you may also have bone and muscle problems as well as increased risk of heart attacks and strokes if the blood levels remain high. Most products containing phosphates and greater than nutritional allowances of vitamin D should generally be discontinued for one week before starting treatment with burosumab. Talk to your doctor if you have any questions or concerns. During treatment, phosphorus blood levels should be closely monitored, which will allow your doctor to determine when a dose adjustment or an interruption in treatment may be required. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

sodium biphosphate food

Applies to: Visicol (sodium biphosphate / sodium phosphate)

Oral medications may not be properly absorbed when they are taken within one hour before starting sodium biphosphate for bowel cleansing. Talk to your doctor or pharmacist to see if you should adjust the dosing schedule of your other medications before you begin bowel cleansing treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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