Marcaine HCl Interactions
There are 135 drugs known to interact with Marcaine HCl (bupivacaine), along with 3 disease interactions. Of the total drug interactions, 23 are major, 107 are moderate, and 5 are minor.
- View all 135 medications that may interact with Marcaine HCl
- View Marcaine HCl disease interactions (3)
Most frequently checked interactions
View interaction reports for Marcaine HCl (bupivacaine) and the medicines listed below.
- acetaminophen / oxycodone
- Adderall (amphetamine / dextroamphetamine)
- Aimovig (erenumab)
- albuterol
- Ambien (zolpidem)
- amoxicillin / clavulanate
- Ativan (lorazepam)
- baclofen
- Benadryl (diphenhydramine)
- clobetasol topical
- cyclobenzaprine
- Cymbalta (duloxetine)
- diazepam
- diphenhydramine
- docusate
- doxycycline
- EpiPen (epinephrine)
- famotidine
- gabapentin
- hydrochlorothiazide
- hydrochlorothiazide / losartan
- Lamictal (lamotrigine)
- Lyrica (pregabalin)
- melatonin
- montelukast
- omeprazole
- ondansetron
- Percocet 5 / 325 (acetaminophen / oxycodone)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Marcaine HCl disease interactions
There are 3 disease interactions with Marcaine HCl (bupivacaine) which include:
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- During pregnancy
- Drug class: local injectable anesthetics
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.