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Drug Interactions between Breo Ellipta and labetalol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

labetalol vilanterol

Applies to: labetalol and Breo Ellipta (fluticasone / vilanterol)

Using labetalol together with vilanterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, labetalol can sometimes cause narrowing of the airways, which may worsen your breathing problems or trigger severe asthmatic attacks. Labetalol is normally not recommended if you have asthma, a history of asthma, or severe chronic obstructive pulmonary disease (COPD). Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact or are less likely to interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

fluticasone vilanterol

Applies to: Breo Ellipta (fluticasone / vilanterol) and Breo Ellipta (fluticasone / vilanterol)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

labetalol food

Applies to: labetalol

Labetalol and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

labetalol food

Applies to: labetalol

Using labetalol together with multivitamin with minerals may decrease the effects of labetalol. Separate the administration times of labetalol and multivitamin with minerals by at least 2 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.