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Drug Interactions between boceprevir and sirolimus topical

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

boceprevir sirolimus topical

Applies to: boceprevir and sirolimus topical

Some of the medication in sirolimus topical may be absorbed into the bloodstream following local application. It is possible that use of boceprevir may further increase blood levels of the medication by interfering with its clearance from your body. You may be more likely to experience serious side effects such as diminished immune function, increased risk of infections, increased cholesterol and lipid levels in the blood, and lung or breathing problems. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

boceprevir food

Applies to: boceprevir

Food significantly increases the absorption of boceprevir. You should take each dose of boceprevir with a meal or light snack. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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