Drug interactions between bicalutamide and Miradon
| Results for the following 2 drugs: |
|---|
| bicalutamide |
| Miradon (anisindione) |
Interactions between your selected drugs
anisindione ↔ bicalutamide
Applies to:Miradon (anisindione) and bicalutamide
In vitro studies have shown that bicalutamide can displace coumarin anticoagulants such as warfarin from protein-binding sites, theoretically resulting in enhanced anticoagulant effects. PT should be monitored closely when bicalutamide is initiated in patients already receiving coumarin anticoagulants. The anticoagulant dosage should be adjusted as needed. Patients should be advised to notify their physicians if they experience any signs of excessive anticoagulation, such as unusual or prolonged bleeding, bruising, vomiting, change in stool or urine color, headache, dizziness, or weakness.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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