Drug Interactions between Baraclude and Sandimmune
This report displays the potential drug interactions for the following 2 drugs:
- Baraclude (entecavir)
- Sandimmune (cyclosporine)
Interactions between your drugs
cycloSPORINE entecavir
Applies to: Sandimmune (cyclosporine) and Baraclude (entecavir)
CycloSPORINE can affect kidney function and may increase the blood levels and effects of entecavir when used together. Contact your doctor if you experience increased side effects or your condition changes. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you experience extreme tiredness or weakness, dizziness, lightheadedness, muscle pain, difficulty breathing, stomach pain, nausea, vomiting, and/or a fast or irregular heart beat, as these may be signs and symptoms of a serious medical condition known as lactic acidosis that can sometimes occur during treatment with medications like entecavir. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
cycloSPORINE food
Applies to: Sandimmune (cyclosporine)
Grapefruit and grapefruit juice can increase the levels of cycloSPORINE in your body and should generally not be consumed during treatment. High blood levels of cycloSPORINE can lead to increased risk of serious side effects on kidney, liver, and nervous system functions. If you regularly consume grapefruits or grapefruit juice, you should be monitored for side effects and/or changes in cycloSPORINE levels. However, do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. You should also take cycloSPORINE on a consistent schedule with regard to time of day and relation to meals. Let your doctor know if you experience fever, rash, nausea, vomiting, abdominal pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes), decreased urination, excessive thirst, swelling, weight gain, dizziness, fatigue, weakness, headache, blurred vision, numbness/burning/tingling in the hand and feet, tremors, or convulsions, as they may be symptoms caused by excessive effects of cycloSPORINE.
entecavir food
Applies to: Baraclude (entecavir)
You may experience reduced absorption of entecavir in the presence of food. Take entecavir on an empty stomach 2 hours before or 2 hours after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication. It is important to take entecavir regularly to get the most benefit.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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