Drug interactions between Aspirin Low Strength and potassium citrate
Results for the following 2 drugs: |
|
|---|---|
| Aspirin Low Strength (aspirin) | |
| potassium citrate | |
Interactions between your selected drugs
aspirin ⇔ potassium citrate
Applies to: Aspirin Low Strength (aspirin) and potassium citrate
MONITOR: Agents that cause urinary alkalinization can reduce serum salicylate concentrations in patients receiving anti-inflammatory dosages of aspirin or other salicylates. The mechanism involves reduction in salicylate renal tubular reabsorption due to increased urinary pH, resulting in increased renal salicylate clearance especially above urine pH of 7. This interaction is sometimes exploited in the treatment of salicylate toxicity.
MANAGEMENT: Patients treated chronically with urinary alkalinizers and large doses of salicylates (i.e. 3 g/day or more) should be monitored for potentially diminished or inadequate analgesic and anti-inflammatory effects, and the salicylate dosage adjusted if necessary.
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