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Drug Interactions between asparaginase escherichia coli and prednisolone

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

prednisoLONE asparaginase Escherichia coli

Applies to: prednisolone and asparaginase escherichia coli

Using prednisoLONE together with asparaginase Escherichia coli may increase your blood sugar levels. Also, this combination may increase your risks of bone-tissue death (osteonecrosis), bleeding or blood clots. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if you have symptoms of high blood sugar such as increased thirst, increased hunger, and increased urination. Also, contact your doctor if you experience bone pain or any unusual bleeding or bruising; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds. Also be alert to potential signs and symptoms of blood clots such as chest pain, shortness of breath, sudden loss of vision, or pain, redness or swelling in an extremity, and seek immediate medical attention if they occur. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

asparaginase Escherichia coli food

Applies to: asparaginase escherichia coli

Talk to your doctor before using asparaginase Escherichia coli together with ethanol. Combining these medications may increase the risk of side effects such as liver damage. You may need more frequent monitoring by your doctor to safely use both medications. Let your doctor know immediately if you develop right upper quadrant pain, increasing abdominal size, fever, swelling, rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.