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Drug Interactions between aminophylline and budesonide / formoterol / glycopyrrolate

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

aminophylline budesonide

Applies to: aminophylline and budesonide / formoterol / glycopyrrolate

Using aminophylline together with budesonide may cause hypokalemia (low blood potassium) and increased aminophylline levels. Contact your doctor if you experience weakness, listlessness, confusion, tingling of the extremities, or feelings of heaviness in the legs. Signs and symptoms of too much aminophylline include nausea, vomiting, diarrhea, headache, restlessness, insomnia, and irregular heartbeat. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aminophylline formoterol

Applies to: aminophylline and budesonide / formoterol / glycopyrrolate

Using aminophylline together with formoterol may increase cardiovascular side effects such as heart palpitations, increased heart and pulse rates, and blood pressure elevations. Combining these medications may also increase the risk of developing hypokalemia, or low blood potassium. Although the hypokalemia associated with these drugs is generally mild and does not cause problems, severe cases can occasionally lead to muscle weakness, paralysis, breathing and swallowing difficulties (due to muscle paralysis), and irregular heart rhythm. Side effects may be more likely if you are receiving formoterol or similar medications in the nebulized, oral, or injectable form. In addition, these medications given orally or by injection may sometimes reduce the blood levels and effects of aminophylline. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Let your doctor know if your breathing worsens or you experience nausea, vomiting, constipation, abdominal cramping, confusion, dizziness, lightheadedness, fainting, muscle weakness, muscle cramps, numbness, tingling, rapid heartbeat, chest pain, and/or swelling in the legs or feet, as these may be symptoms of hypokalemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

budesonide formoterol

Applies to: budesonide / formoterol / glycopyrrolate and budesonide / formoterol / glycopyrrolate

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

budesonide food

Applies to: budesonide / formoterol / glycopyrrolate

You should avoid the regular consumption of large amounts of grapefruits and grapefruit juice while taking budesonide. Grapefruit can raise the levels of budesonide in your body and lead to increased side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Moderate

glycopyrrolate food

Applies to: budesonide / formoterol / glycopyrrolate

Ask your doctor before using glycopyrrolate together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aminophylline food

Applies to: aminophylline

Both aminophylline and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.