Acetaminophen/guaifenesin/phenylephrine Interactions
There are 309 drugs known to interact with acetaminophen/guaifenesin/phenylephrine, along with 7 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 34 are major, 254 are moderate, and 21 are minor.
- View all 309 medications that may interact with acetaminophen/guaifenesin/phenylephrine
- View acetaminophen/guaifenesin/phenylephrine alcohol/food interactions (2)
- View acetaminophen/guaifenesin/phenylephrine disease interactions (7)
Most frequently checked interactions
View interaction reports for acetaminophen / guaifenesin / phenylephrine and the medicines listed below.
- Allegra (fexofenadine)
- Allegra-D 24 Hour Allergy & Congestion (fexofenadine / pseudoephedrine)
- Beano (alpha-d-galactosidase)
- Benadryl (diphenhydramine)
- Benadryl Allergy (diphenhydramine)
- Dramamine (dimenhydrinate)
- Eliquis (apixaban)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Flovent HFA (fluticasone)
- Klonopin (clonazepam)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Mucinex (guaifenesin)
- Mucinex D (guaifenesin / pseudoephedrine)
- Norco (acetaminophen / hydrocodone)
- Pamprin Multi-Symptom Menstrual Relief (acetaminophen / pamabrom / pyrilamine)
- Phenergan (promethazine)
- ProAir HFA (albuterol)
- Pulmicort Flexhaler (budesonide)
- Restasis (cyclosporine ophthalmic)
- Singulair (montelukast)
- Toradol IM (ketorolac)
- Vicks Dayquil Cold & Flu Relief (acetaminophen / dextromethorphan / phenylephrine)
- Vicks NyQuil Cold & Flu Nighttime Relief (acetaminophen / dextromethorphan / doxylamine)
- Vicks NyQuil Severe Cold & Flu (acetaminophen / dextromethorphan / doxylamine / phenylephrine)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xopenex HFA (levalbuterol)
- Zyrtec (cetirizine)
Acetaminophen/guaifenesin/phenylephrine alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen / guaifenesin / phenylephrine.
Acetaminophen/guaifenesin/phenylephrine disease interactions
There are 7 disease interactions with acetaminophen / guaifenesin / phenylephrine which include:
More about acetaminophen / guaifenesin / phenylephrine
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- Drug images
- Side effects
- Dosage information
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.