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Drug Interactions between Aceon and estramustine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

estramustine perindopril

Applies to: estramustine and Aceon (perindopril)

Using estramustine together with perindopril may cause angioedema, a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet. Each medication alone can also cause angioedema, but the risk may be increased when they are combined. Angioedema can occur with the first dose of medication or after many doses. You should discontinue the medications and seek immediate medical attention if you develop symptoms of angioedema or have difficulty swallowing or breathing. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

estramustine food

Applies to: estramustine

Food and milk may decrease the levels of estramustine in your body. It is recommended that estramustine be taken at least 1 hour before or 2 hours after meals. This will make it easier for your body to absorb the medication. Estramustine should not be taken with milk or calcium containing products.

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Moderate

perindopril food

Applies to: Aceon (perindopril)

It is recommended that if you are taking perindopril you should be advised to avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking perindopril, unless your doctor has told you to.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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