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Hematopoietic stem cell mobilizer

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Hematopoietic stem cell mobilizer binds to the CXCR4 chemokine receptor and inhibits the binding of its ligand, stromal cell-derived factor-1-alpha (SDF-1-alpha). This leads to mobilization of hematopoietic stem cells to the peripheral blood. The hematopoietic stem cells (CD34+ cells) are collected from the peripheral blood and used for autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma. Hematopoietic stem cells produce all types of blood cells so autologous transplantation restores normal production of the blood cells.

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plerixafor systemic (Pro, More...)
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Medical conditions associated with hematopoietic stem cell mobilizer: