Zituvio Dosage

Recommended Dosage

The recommended dosage of ZITUVIO is 100 mg orally once daily. ZITUVIO can be taken with or without food.

Recommendations for Use in Renal Impairment

Assess renal function prior to initiation of ZITUVIO and periodically thereafter.

For patients with an estimated glomerular filtration rate [eGFR] greater than or equal to 45 mL/min/1.73 m2to less than 90 mL/min/1.73 m2, no dosage adjustment for ZITUVIO is required.

For patients with moderate renal impairment (eGFR greater than or equal to 30 mL/min/1.73 m2to less than 45 mL/min/1.73 m2), the dosage of ZITUVIO is 50 mg once daily.

For patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m2) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dosage of ZITUVIO is 25 mg once daily. ZITUVIO may be administered without regard to the timing of dialysis.