Sirolimus Topical Dosage

Medically reviewed by Drugs.com. Last updated on Sep 21, 2022.

Usual Adult Dose for Angiofibroma

Usual dose: Apply to the skin of the face affected with angiofibroma twice daily, in the morning and at bedtime.
Maximum dose: 800 mg (2.5 cm)

Comment:
If symptoms do not improve after 12 weeks of treatment, reassess the need for continuation of this drug.

Use: Topical treatment of facial angiofibroma associated with tuberous sclerosis

Usual Pediatric Dose for Angiofibroma

Usual dose: Apply to the skin of the face affected with angiofibroma twice daily in the morning and at bedtime.
Maximum dose: 600 mg (2 cm) for patients 6 to 11 years of age, 800 mg (2.5 cm) for patients 12 to 18 years of age

Comment:
If symptoms do not improve after 12 weeks of treatment, reassess the need for continuation of this drug.

Use: Topical treatment of facial angiofibroma associated with tuberous sclerosis

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
Contraindicated in patients with a known history of hypersensitivity to sirolimus or any other component.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Bandages, dressings, or wraps should not be used on the skin being treated with sirolimus topical.

Storage requirements:

• Store at 2C to 8C (36F to 46F). Protect from light.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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