Morrhuate Sodium Dosage

Usual Adult Dose for Varicose Vein

Small to medium veins: 50 to 100 mg (1 to 2 mL of the 5% injection) intravenously, repeated at 5- to 7-day intervals.

Large veins: 150 to 250 mg (3 to 5 mL of the 5% injection) intravenously, repeated at 5- to 7-day intervals.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Sloughing and necrosis of tissue may occur following extravasation.

Anaphylactoid and allergic reactions have occurred. Some clinicians recommend injection of 0.25 to 1 mL of 5% morrhuate sodium injection into a varicosity 24 hours before administration of a large dose.

Dialysis

Data not available

Other Comments

Following injection of morrhuate sodium, the vein promptly becomes hard and swollen for 2 to 4 inches, depending on the size and response of the vein. After 24 hours, the vein is hard and slightly tender to the touch. The skin around the injection becomes light-bronze; this color usually disappears shortly. An aching sensation and feeling of stiffness usually occurs and lasts approximately 48 hours.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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