Migranal Dosage
Generic name: dihydroergotamine mesylate
Dosage form: nasal spray
This dosage information does not include all the information needed to use Migranal safely and effectively. See full prescribing information for Migranal.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
The solution used in Migranal® (dihydroergotamine mesylate, USP) Nasal Spray (4 mg/mL) is intended for intranasal use and must not be injected.
In clinical trials, Migranal® (dihydroergotamine mesylate, USP) Nasal Spray has been effective for the acute treatment of migraine headaches with or without aura. One spray (0.5 mg) of Migranal® (dihydroergotamine mesylate, USP) Nasal Spray should be administered in each nostril. Fifteen minutes later, an additional one spray (0.5 mg) of Migranal® (dihydroergotamine mesylate, USP) Nasal Spray should be administered in each nostril, for a total dosage of four sprays (2.0 mg) of Migranal® (dihydroergotamine mesylate, USP) Nasal Spray. Studies have shown no additional benefit from acute doses greater than 2.0 mg for a single migraine administration. The safety of doses greater than 3.0 mg in a 24 hour period and 4.0 mg in a 7 day period has not been established.
Migranal® (dihydroergotamine mesylate, USP) Nasal Spray, should not be used for chronic daily administration.
Prior to administration, the pump must be primed (i.e., squeeze 4 times) before use. (See administration instructions) Once the nasal spray applicator has been prepared, it should be discarded (with any remaining drug in opened vial ) after 8 hours.
Prior to administration, the pump must be primed (i.e., squeeze 4 times) before use. (See administration instructions)
Once the nasal spray applicator has been prepared, it should be discarded (with any remaining drug in opened vial after 8 hours).


