Ibutilide Dosage

This dosage information may not include all the information needed to use Ibutilide safely and effectively. See additional information for Ibutilide.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Atrial Fibrillation

Initial dose:
60 or more Kg: 1 mg IV administered slowly over 10 minutes.

less than 60 Kg: 0.01 mg/kg IV administered slowly over 10 minutes.

Usual Adult Dose for Atrial Flutter

Initial dose:
60 or more Kg: 1 mg IV administered slowly over 10 minutes.

less than 60 Kg: 0.01 mg/kg IV administered slowly over 10 minutes.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

The dose may be repeated if the arrhythmia does not terminate within 10 minutes after the end of the initial infusion.

Precautions

Patients should have telemetry monitoring for at least 4 hours. Other concomitant medications which prolong the QTc interval may increase the incidence of proarrhythmias.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

Correct hypokalemia and hypomagnesemia prior to cardioversion.

Ibutilide appears to be most effective for cardioversion of atrial fibrillation in patients with coronary artery disease and in patients without mitral valve disease and/or markedly enlarged left atrium.

Pretreatment with IV magnesium sulfate may prevent increases in QT and QTc interval 30 minutes after the last dose of ibutilide.

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