Glyxambi Dosage
Generic name: EMPAGLIFLOZIN 10mg, LINAGLIPTIN 5mg
Dosage form: tablet, film coated
Drug class: Antidiabetic combinations
Medically reviewed by Drugs.com. Last updated on Jun 10, 2024.
Testing Prior to Initiation of GLYXAMBI
- Assess renal function before initiating GLYXAMBI and as clinically indicated [see Warnings and Precautions (5.3)].
- Assess volume status. In patients with volume depletion, correct this condition before initiating GLYXAMBI [see Warnings and Precautions (5.3) and Use in Specific Populations (8.5, 8.6)].
Recommended Dosage and Administration
The recommended dosage of GLYXAMBI is 10 mg empagliflozin/5 mg linagliptin once daily in the morning, taken with or without food. GLYXAMBI may be increased to 25 mg empagliflozin/5 mg linagliptin once daily for additional glycemic control.
Dosage Recommendations in Patients with Renal Impairment
GLYXAMBI is not recommended for use in patients with an eGFR less than 30 mL/min/1.73 m2 and contraindicated in patients on dialysis [see Indications and Usage (1), Contraindications (4), Warnings and Precautions (5.3), and Use in Specific Populations (8.6)].
Recommendations Regarding Missed Dose
- If a dose is missed, instruct patients to take the dose as soon as possible.
- Do not double up the next dose.
Temporary Interruption for Surgery
Withhold GLYXAMBI for at least 3 days, if possible, prior to major surgery or procedures associated with prolonged fasting. Resume GLYXAMBI when the patient is clinically stable and has resumed oral intake [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.2)].
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