Diphtheria And Tetanus Toxoids / Pertussis, Acellular Dosage

Medically reviewed by Drugs.com. Last updated on Oct 3, 2023.

Applies to the following strengths: 15 units-5 units-23 mcg/0.5 mL; 6.7 units-5 units-46.8 mcg/0.5 mL; 25 units-10 units-58 mcg/0.5 mL

Usual Pediatric Dose for:

Diphtheria Prophylaxis
Pertussis Prophylaxis
Tetanus Prophylaxis

Usual Pediatric Dose for Diphtheria Prophylaxis

6 weeks to 6 years: 0.5 mL intramuscularly at 2, 4, and 6 months old, then again between 15 to 20 months old and at 4 to 6 years of age

Comments:

The first dose may be given as early as 6 weeks of age.

Usual Pediatric Dose for Pertussis Prophylaxis

6 weeks to 6 years: 0.5 mL intramuscularly at 2, 4, and 6 months old, then again between 15 to 20 months old and at 4 to 6 years of age

Comments:

The first dose may be given as early as 6 weeks of age.

Usual Pediatric Dose for Tetanus Prophylaxis

6 weeks to 6 years: 0.5 mL intramuscularly at 2, 4, and 6 months old, then again between 15 to 20 months old and at 4 to 6 years of age

Comments:

The first dose may be given as early as 6 weeks of age.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

Severe allergic reaction (e.g. anaphylaxis) to any ingredient or to other diphtheria toxoid-, tetanus toxoid-, or pertussis-containing vaccine
Encephalopathy within 7 days of a previous pertussis-containing vaccine
Progressive neurological disorders

Safety and efficacy have not been established in patients younger than 6 weeks or older than 6 years (prior to seventh birthday); this drug is not recommended for use in these patients.

To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS) at: https://vaers.hhs.gov

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Do not administer intravenously, intradermally, or subcutaneously.
The anterolateral aspect of the thigh is the preferred administration site in children under 12 months old; the deltoid of the upper arm can be used for older children.