Cystografin Dosage

Generic name: diatrizoate meglumine
Dosage form: injection, solution

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Preparation of the patient: Appropriate preparation is desirable for optimal results. A laxative the night before the examination and a low residue diet the day before the procedure are recommended.

Dosage: The dose for retrograde use in cystography and voiding cystourethrography ranges from 25 to 300 mL depending on the age of the patient and the degree of bladder irritability; amounts greater than 300 mL may be used if the bladder capacity allows. Best results are obtained when the bladder is filled with the contrast agent. If desired, the preparation may be diluted with sterile water or sterile saline as indicated in the table below.

Administration: After sterile catheterization, the bladder should be filled to capacity with Cystografin using a suitable sterile administration set. Care should be taken to avoid using excessive pressure. The presence of bladder discomfort or reflux and/or spontaneous voiding usually indicates that the bladder is full.

Radiography: The commonly employed radiographic techniques should be used. A scout film is recommended before the contrast agent is administered.

Dilution Table
USE DILUTED SOLUTIONS IMMEDIATELY
100 mL Bottle  
Sterile Water or Sterile Saline Added % Diatrizoate Meglumine w/v % Organically Bound Iodine w/v Total Volume
0 mL 30.0 14.1 100 mL
25 mL 24.0 11.3 125 mL
50 mL 20.0 9.4 150 mL
67 mL 18.0 8.5 167 mL
300 mL Bottle  
Sterile Water or Sterile Saline Added  
0 mL 30.0 14.1 300 mL
50 mL 25.7 12.1 350 mL
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