Collagenase Topical Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Keratosis

Apply to affected areas once daily or as necessary for dressing changes.

Usual Pediatric Dose for Keratosis

Apply to affected areas once daily or as necessary for dressing changes.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The optimal pH range for collagenase is 6 to 8. Higher or lower pH conditions will decrease collagenase activity and appropriate precautions should be taken.

The enzymatic activity of collagenase is adversely effected by detergents, hexachlorophene, and heavy metal ions such as those found in some antiseptics. Cleansing materials such as hydrogen peroxide, Dakin's solution, and sterile saline are compatible with collagenase ointment.

Dialysis

Data not available

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