Chlorpheniramine / Dextromethorphan / Pseudoephedrine Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough and Nasal Congestion

chlorpheniramine/dextromethorphan/PSE 2 mg-15 mg-15 mg/5 mL oral liquid: 10 mL orally four times daily

chlorpheniramine/dextromethorphan/PSE 4 mg-30 mg-30 mg/5 mL oral suspension, extended release or
chlorpheniramine/dextromethorphan/PSE 6 mg-30 mg-30 mg/5 mL oral suspension, extended release or
chlorpheniramine/dextromethorphan/PSE 5 mg-25 mg-75 mg/5 mL oral suspension, extended release: 5 to 10 mL orally every 12 hours

chlorpheniramine/dextromethorphan/PSE 2 mg-10 mg-30 mg oral tablet, chewable:
2 tablets orally every 4 to 6 hours not to exceed 4 doses in 24 hours.

Usual Pediatric Dose for Cough and Nasal Congestion

chlorpheniramine/dextromethorphan/PSE 2 mg-15 mg-15 mg/5 mL oral liquid:
12 yrs or older: 10 mL orally four times daily
6 yrs to 11 yrs: 5 mL orally four times daily
2 yrs to 5 yrs: 2.5 mL orally four times daily

chlorpheniramine/dextromethorphan/PSE 4 mg-30 mg-30 mg/5 mL oral suspension, extended release or
chlorpheniramine/dextromethorphan/PSE 6 mg-30 mg-30 mg/5 mL oral suspension, extended release or
chlorpheniramine/dextromethorphan/PSE 5 mg-25 mg-75 mg/5 mL oral suspension, extended release:
12 yrs or older: 5 to 10 mL orally every 12 hours
6 yrs to 11 yrs: 2.5 to 5 mL orally every 12 hours
2 yrs to 5 yrs: 2.5 mL orally every 12 hours

chlorpheniramine/dextromethorphan/PSE 0.8 mg-3 mg-9 mg/mL oral liquid:
25 to 36 months: 1 mL orally 4 times a day. Do not exceed 4 doses in a 24 hour period.
13 to 24 months: 0.75 mL orally 4 times a day. Do not exceed 4 doses in a 24 hour period.
6 to 12 months: 0.5 mL orally 4 times a day. Do not exceed 4 doses in a 24 hour period.

chlorpheniramine/dextromethorphan/PSE 2 mg-10 mg-30 mg oral tablet, chewable:
6 yrs to 11 yrs: 1 tablet orally every 4 to 6 hours not to exceed 4 doses in 24 hours.
12 yrs or older: 2 tablets orally every 4 to 6 hours not to exceed 4 doses in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Dialysis

Data not available

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