Chlorpheniramine / Dextromethorphan / Phenylephrine Dosage

Medically reviewed by Drugs.com. Last updated on Aug 3, 2023.

Applies to the following strengths: 2 mg-15 mg-10 mg/5 mL; 2 mg-10 mg-5 mg/5 mL; 4 mg-15 mg-12.5 mg/5 mL; 1 mg-5 mg-2.5 mg/5 mL; 4 mg-15 mg-10 mg/5 mL; 4 mg-10 mg-10 mg; 1 mg-3 mg-3.5 mg/mL; 2 mg-15 mg-5 mg/5 mL; 2 mg-15 mg-6 mg/5 mL; 8 mg-30 mg-20 mg; 1 mg-3 mg-1.5 mg/mL; 1 mg-3 mg-2 mg/mL; 0.75 mg-2.75 mg-1.75 mg/mL; 2 mg-10 mg-5 mg; 4 mg-10 mg-10 mg/30 mL; 4 mg-12.5 mg-10 mg/5 mL; 4 mg-20 mg-10 mg/10 mL; 3.5 mg-29 mg-10 mg; 2 mg-30 mg-20 mg; 1 mg-2.5 mg-2.5 mg/mL

Usual Adult Dose for Cough and Nasal Congestion

Chlorpheniramine/dextromethorphan/phenylephrine 1 mg-5 mg-2.5 mg/5 mL oral liquid
20 mL orally every 4 hours not to exceed 6 doses daily.

Chlorpheniramine/dextromethorphan/phenylephrine 2 mg-10 mg-5 mg/5 mL oral liquid:
10 mL orally every 4 hours not to exceed 6 doses daily.

Chlorpheniramine/dextromethorphan/phenylephrine 2 mg-30 mg-20 mg oral tablet, extended release:
1 to 2 tablets orally every 12 hours not to exceed 4 tablets daily.

Chlorpheniramine/dextromethorphan/phenylephrine 4 mg-15 mg-12.5 mg/5 mL oral syrup:
5 mL orally every 4 to 6 hours not to exceed 30 mL daily.

Chlorpheniramine/dextromethorphan/phenylephrine 8 mg-30 mg-20 mg oral tablet, extended release:
1 to 2 tablets orally every 12 hours not to exceed 3 tablets daily.

Usual Pediatric Dose for Cough and Nasal Congestion

Chlorpheniramine/dextromethorphan/phenylephrine 0.75 mg-2.75 mg-1.75 mg/mL oral drops:
2 to 5 years: 1 mL orally every 4 to 6 hours not to exceed 4 doses daily.
6 to 12 years: 2 mL orally every 4 to 6 hours not to exceed 4 doses daily.

Chlorpheniramine/dextromethorphan/phenylephrine 1 mg-3 mg-1.5 mg/mL oral liquid:
2 to 5 years: 1 mL orally every 4 to 6 hours not to exceed 4 doses daily.
6 to 12 years: 2 mL orally every 4 to 6 hours not to exceed 4 doses daily.

Chlorpheniramine/dextromethorphan/phenylephrine 1 mg-3 mg-2 mg/mL oral drops:
2 to 5 years: 1 mL orally every 4 to 6 hours.
6 to 11 yrs: 2 mL orally every 4 to 6 hours.

Chlorpheniramine/dextromethorphan/phenylephrine 1 mg-3 mg-3.5 mg/mL oral liquid:
6 to 11 months: 0.75 mL orally 4 times daily.
1 to 2 years: 1 mL orally 4 times daily.

Chlorpheniramine/dextromethorphan/phenylephrine 1 mg-5 mg-2.5 mg/5 mL oral liquid
6 to 11 years: 10 mL orally every 4 hours not to exceed 6 doses daily.
12 years or older: 20 mL orally every 4 hours not to exceed 6 doses daily.

Chlorpheniramine/dextromethorphan/phenylephrine 2 mg-10 mg-5 mg/5 mL oral liquid:
6 to 11 years: 5 mL orally every 4 hours not to exceed 6 doses daily.
12 years or older: 10 mL orally every 4 hours not to exceed 6 doses daily.

Chlorpheniramine/dextromethorphan/phenylephrine 2 mg-30 mg-20 mg oral tablet, extended release:
6 to 11 years: 1 tablet orally every 12 hours not to exceed 2 tablets daily.
12 years or older: 1 to 2 tablets orally every 12 hours not to exceed 4 tablets daily.

Chlorpheniramine/dextromethorphan/phenylephrine 4 mg-15 mg-12.5 mg/5 mL oral syrup:
2 to 5 years: 1.25 mL orally every 4 to 6 hours not to exceed 7.5 mL daily.
6 to 11 yrs: 2.5 mL orally every 4 to 6 hours not to exceed 15 mL daily.
12 years or older: 5 mL orally every 4 to 6 hours not to exceed 30 mL daily.

Chlorpheniramine/dextromethorphan/phenylephrine 8 mg-30 mg-20 mg oral tablet, extended release:
12 years or older: 1 to 2 tablets orally every 12 hours not to exceed 3 tablets daily.