Benzocaine / Trimethobenzamide Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nausea/Vomiting

200 mg rectally 3 to 4 times a day as needed.

Usual Pediatric Dose for Nausea/Vomiting

1 to 12 years: 15 to 20 mg/kg/day (400 to 500 mg/m2/day) rectally administered in equally divided doses 3 to 4 times a day as needed.

Alternatively:
1 to 12 years:
< 13.6 kg (30 lbs): 100 mg rectally 3 to 4 times a day as needed.
13.6 to 41 kg (30 to 90 lbs): 100 to 200 mg rectally 3 to 4 times a day as needed.

Precautions

Avoid overhydrating patients on trimethobenzamide since it may result in cerebral edema.

Trimethobenzamide may cause drowsiness and may impair a person ability to operate machinery. Patients should be advised not to take this drug with alcohol.

The antiemetic effect of trimethobenzamide may make the diagnosis of conditions such as appendicitis and drug overdose more difficult.

Neurologic reactions resulting from trimethobenzamide use may be similar to signs and symptoms accompanying such disorders as acute febrile encephalitis, Reye's syndrome, gastroenteritis, dehydration and electrolyte imbalance. This drug should be used with caution in patients who have such disorders, especially in children and the elderly or debilitated.

Other Comments

Patients should be advised about that this combination product contains an ester type anesthetic.

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