Atogepant Dosage

Medically reviewed by Drugs.com. Last updated on Oct 10, 2023.

Usual Adult Dose for Migraine Prophylaxis

Episodic migraine: 10 mg, 30 mg, or 60 mg orally once a day
Chronic migraine: 60 mg orally once a day

Use: For the preventative treatment of episodic and chronic migraine

Renal Dose Adjustments

• Mild to Moderate Renal Dysfunction : No adjustment recommended
• Severe Renal Dysfunction and ESRD (CrCl less than 30 mL/min):
• Episodic migraine: 10 mg orally once a day
• Chronic migraine: Avoid use

Liver Dose Adjustments

• Mild to moderate hepatic impairment : No adjustment recommended
• Severe hepatic impairment : Avoid use

Dose Adjustments

Elderly: Dose selection should be cautious, generally starting at the low end of the dosing range.

Concomitant CYP450 3A4 Inducers/Inhibitors:

• Strong CYP450 3A4 inhibitors:
• Episodic migraine: 10 mg orally once a day
• Chronic migraine: Avoid use
• Strong, moderate, or weak CYP450 3A4 inducers:
• Episodic migraine: 30 mg or 60 mg orally once a day
• Chronic migraine: Avoid use
• OATP inhibitors:
• Episodic migraine: 10 mg or 30 mg orally once a day
• Chronic migraine: 30 mg orally once a day

Precautions

CONTRAINDICATIONS:

• History of hypersensitivity to this drug or any of the components

Report Adverse Reactions at www.fda.gov/medwatch.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

For patients undergoing intermittent dialysis: 10 mg orally once a day with dose to be administered after dialysis

Other Comments

Administration advice:

• Take orally once a day with or without food.

Storage:

• Store between 20C and 25C (68F and 77F), with excursions permitted between 15C and 30C (59F and 86F).

Patient advice:

• Read the Patient Information and Instructions for Use.
• Patients should understand that this drug may interact with other drugs and dose adjustments may be necessary; patients should be instructed to report use of all prescription medications, over-the-counter medications, herbal products, and/or grapefruit to their healthcare provider.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer