Aminocaproic Acid Dosage

Medically reviewed by Drugs.com. Last updated on May 2, 2024.

Applies to the following strengths: 500 mg; 1.25 g/5 mL; 250 mg/mL; 1000 mg

Usual Adult Dose for:

Fibrinolytic Bleeding

Additional dosage information:

Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments

Usual Adult Dose for Fibrinolytic Bleeding

IV: 4 to 5 g IV infusion during the first hour of treatment, followed by a continuous infusion of 1 g/hr.
Oral: 5 g orally during the first hour of treatment, followed by a continuous rate of 1 g/hr (tablets) or 1.25 g/hr (oral solution).

Duration of therapy: Usually continued for about 8 hours or until bleeding controlled.

Use: To enhance hemostasis when fibrinolysis contributes to bleeding.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice: Rapid injection of undiluted drug into a vein is not recommended.

IV compatibility: Usual compatible IV vehicles may be used (e.g., sterile water for injection, sodium chloride for Injection, 5% dextrose or Ringer's injection). The resultant solution with sterile water for injection is hypo-osmolar.

Monitoring:

Hematologic: Tests to determine the amount of fibrinolysis present.
Musculoskeletal: Creatine phosphokinase (CPK) levels in patients taking this drug long-term.