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Evrysdi Disease Interactions

There is 1 disease interaction with Evrysdi (risdiplam).

Moderate

Risdiplam (applies to Evrysdi) hepatic dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

The pharmacokinetics and safety of risdiplam in patients with severe hepatic impairment (Child-Pugh class C) have not been studied. In patients with mild or moderate hepatic impairment, clinically meaningful differences have not been observed.

References

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
  2. (2020) "Product Information. Evrysdi (risdiplam)." Genentech

Evrysdi drug interactions

There are 11 drug interactions with Evrysdi (risdiplam).


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.