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Futibatinib Disease Interactions

There are 2 disease interactions with futibatinib.

Moderate

Futibatinib (applies to futibatinib) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

The pharmacokinetics of futibatinib has not been studied in patients with moderate or severe hepatic impairment (total bilirubin greater than 1.5 x ULN and any AST).

References

  1. (2022) "Product Information. Lytgobi (futibatinib)." Taiho Oncology, Inc., 1
Moderate

Futibatinib (applies to futibatinib) renal dysfunction

Moderate Potential Hazard, Moderate plausibility.

The pharmacokinetics of futibatinib has not been studied in patients with severe renal impairment (CrCl 15 to 29 mL/min), renal dialysis in end-stage renal disease (CrCl less than 15 mL/min).

References

  1. (2022) "Product Information. Lytgobi (futibatinib)." Taiho Oncology, Inc., 1

Futibatinib drug interactions

There are 152 drug interactions with futibatinib.

Futibatinib alcohol/food interactions

There is 1 alcohol/food interaction with futibatinib.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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