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Proscar Disease Interactions

There are 2 disease interactions with Proscar (finasteride).

Moderate

5-alpha-reductase inhibitors (applies to Proscar) liver disease

Moderate Potential Hazard, Moderate plausibility.

Finasteride and dutasteride are extensively metabolized by the liver. Therapy with these drugs should be administered cautiously in patients with liver disease as exposure could be higher.

References

  1. "Product Information. Proscar (finasteride)." Merck & Co., Inc PROD (2002):
  2. "Product Information. Duagen (dutasteride)." GlaxoSmithKline Healthcare (2002):
Moderate

Finasteride (applies to Proscar) urinary obstruction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Urinary Tract Obstruction

Patients with large residual urinary volume and/or severely diminished urinary flow should be carefully monitored for obstructive uropathy. These patients may not be candidates for finasteride therapy.

References

  1. "Product Information. Proscar (finasteride)." Merck & Co., Inc PROD (2002):

Proscar drug interactions

There are 27 drug interactions with Proscar (finasteride).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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