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Quviviq Disease Interactions

There are 5 disease interactions with Quviviq (daridorexant).

Major

Daridorexant (applies to Quviviq) narcolepsy

Major Potential Hazard, Moderate plausibility.

Daridorexant is contraindicated in patients with narcolepsy.

References

  1. (2022) "Product Information. Quviviq (daridorexant)." Idorsia Pharmaceuticals US Inc.
Moderate

Daridorexant (applies to Quviviq) alcohol/drug abuse

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Alcoholism, Drug Abuse/Dependence

Patients with a history of abuse or addiction to alcohol or other substances may be at increased risk for abuse of or addiction to daridorexant and should be monitored closely.

References

  1. (2022) "Product Information. Quviviq (daridorexant)." Idorsia Pharmaceuticals US Inc.
Moderate

Daridorexant (applies to Quviviq) COPD/pulmonary impairment

Moderate Potential Hazard, Moderate plausibility.

Daridorexant is a respiratory depressant and should be used with caution if prescribed to patients with impaired respiratory function. This drug has not been studied in patients with moderate to severe sleep apnea requiring CPAP or in patients with severe chronic obstructive pulmonary disease (COPD).

References

  1. (2022) "Product Information. Quviviq (daridorexant)." Idorsia Pharmaceuticals US Inc.
Moderate

Daridorexant (applies to Quviviq) depression/suicidal ideation

Moderate Potential Hazard, Moderate plausibility.

Daridorexant can worsen depression and suicidal thoughts and actions and should be used with caution in patients with depression. These patients should be monitored closely and any preventive measures should be taken.

References

  1. (2022) "Product Information. Quviviq (daridorexant)." Idorsia Pharmaceuticals US Inc.
Moderate

Daridorexant (applies to Quviviq) hepatic dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Daridorexant is not recommended in patients with severe hepatic dysfunction. The maximum recommended dosage in patients with moderate hepatic dysfunction is 25 mg once per night.

References

  1. (2022) "Product Information. Quviviq (daridorexant)." Idorsia Pharmaceuticals US Inc.

Quviviq drug interactions

There are 391 drug interactions with Quviviq (daridorexant).

Quviviq alcohol/food interactions

There are 2 alcohol/food interactions with Quviviq (daridorexant).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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