Chenodeoxycholic acid Disease Interactions
There is 1 disease interaction with chenodeoxycholic acid.
Chenodeoxycholic acid (applies to chenodeoxycholic acid) hepatic or ductal dysfunction
Major Potential Hazard, Moderate plausibility. Applicable conditions: Biliary Cirrhosis, Liver Disease, Cholelithiasis, Cholangitis
Chenodeoxycholic acid is contraindicated in the presence of known hepatocyte dysfunction or bile ductal abnormalities such as intrahepatic cholestasis, primary biliary cirrhosis or sclerosing cholangitis; a gallbladder confirmed as non-visualizing after two consecutive single doses of dye; radiopaque stones; or gallstone complications or compelling reasons for gallbladder surgery including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary gastrointestinal fistula.
References
- (2009) "Product Information. Chenodal (chenodeoxycholic acid)." Manchester Pharmaceutical
Chenodeoxycholic acid drug interactions
There are 62 drug interactions with chenodeoxycholic acid.
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- Drug class: gallstone solubilizing agents
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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