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Agalsidase beta Disease Interactions

There is 1 disease interaction with agalsidase beta.

Moderate

Alpha-galactosidase A proteins (applies to agalsidase beta) cardiac function

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Heart Disease

Appropriate medical support measures should be readily available when administering alpha-galactosidase A enzyme replacement therapy (ERT) due to the potential for severe infusion-associated reactions. Compromised cardiac function may predispose patients to a higher risk of severe complications from infusion-associated reactions. Closely monitor patients with compromised cardiac function during administration of ERT.

References

  1. (2021) "Product Information. Fabrazyme (agalsidase beta)." Genzyme Corporation, SUPPL-5309
  2. (2023) "Product Information. Elfabrio (pegunigalsidase alfa)." Chiesi USA, Inc

Agalsidase beta drug interactions

There are 5 drug interactions with agalsidase beta.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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