sincalide (Intravenous route)

SIN-ka-lide

Commonly used brand name(s)

In the U.S.

  • Kinevac

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Diagnostic Agent

Uses For sincalide

Sincalide belongs to the group of medicines known as diagnostic aids. Diagnostic aids are used to help diagnose certain medical problems. Sincalide is given by injection before tests are done to check if the gallbladder and pancreas are working properly and to help diagnose other problems of these organs.

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The doses of sincalide will be different for different patients and depend on the weight of the patient and on the type of test.

Sincalide is used only under the supervision of a doctor.

Before Using sincalide

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to sincalide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on sincalide have been done only in adult patients, and there is no specific information comparing use of sincalide in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of sincalide in the elderly with use in other age groups.

Pregnancy

Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:

  • Blockage of the intestines or
  • Gallbladder stones—Sincalide may make these conditions worse

Proper Use of sincalide

Dosing

The dose of sincalide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of sincalide. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

sincalide Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare
  • Dizziness, fainting, or lightheadedness
  • increase in blood pressure
  • shortness of breath
  • skin rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal or stomach pain, cramps, or discomfort
  • nausea
Less common or rare
  • Diarrhea
  • dizziness
  • flushing or redness of skin
  • headache
  • increased sweating
  • numbness
  • sneezing
  • urge to have bowel movement
  • vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

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