ocriplasmin (Intraocular route)
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Ophthalmologic Agent
Pharmacologic Class: Proteolytic Enzyme
Uses For ocriplasmin
Ocriplasmin injection is used to treat symptomatic vitreomacular adhesion. Symptomatic vitreomacular adhesion is an eye condition related to aging that may lead to blurring of vision or blindness.
ocriplasmin is only administered by or under the supervision of your doctor.
Before Using ocriplasmin
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ocriplasmin, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to ocriplasmin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of ocriplasmin injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ocriplasmin injection in the elderly.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of ocriplasmin. Make sure you tell your doctor if you have any other medical problems, especially:
- Detached retina (eye disorder) or
- Dyschromatopsia (color vision disorder) or
- Eye infection or
- Glaucoma (increased pressure in the eye) or
- Lens subluxation (partial dislocation of the eye lens)—Use with caution. May make these conditions worse.
Proper Use of ocriplasmin
An eye doctor will give you ocriplasmin as a shot into the eye.
Precautions While Using ocriplasmin
Your eye doctor will want to check your progress at regular visits, especially during the first few days after you receive ocriplasmin.
Serious eye problems may occur with ocriplasmin. Check with your eye doctor right away if your eye becomes red, sensitive to light, or painful, or if you have a change in vision, or feel increased pressure in the eye several days after the injection.
ocriplasmin may cause temporary blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you are not able to see well. If this symptom persists, have your eyes checked by an eye doctor.
ocriplasmin Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:More common
- Bloody eyes
- blurred vision or other change in vision
- decreased vision
- eye pain
- redness of the eye
- seeing flashes or sparks of light
- sensitivity of the eye to light
- Change in color vision
- difficulty seeing at night
- eye discomfort
- loss of vision
- seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
- throbbing pain
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common
- Dry eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: ocriplasmin Intraocular side effects (in more detail)
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