Brexpiprazole Alternatives Compared
Brexpiprazole | Trintellix | Wellbutrin XL |
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Brexpiprazole | Trintellix (vortioxetine) | Wellbutrin XL (bupropion) |
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Prescription only
Brexpiprazole is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression. Most people experience some improvement in their symptoms within 1 to 2 weeks of... View more |
Prescription only
Trintellix may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits serotonin... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression, Seasonal Affective Disorder. Wellbutrin XL may also be used for purposes not listed in this medication guide. |
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More about Brexpiprazole | More about Trintellix (vortioxetine) | More about Wellbutrin XL (bupropion) | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Brexpiprazole has an average rating of 6.5 out of 10 from a total of 480 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 27% reported a negative effect. |
Trintellix has an average rating of 6.0 out of 10 from a total of 1100 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 33% reported a negative effect. |
Wellbutrin XL has an average rating of 7.5 out of 10 from a total of 484 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: brexpiprazole side effects in more detail. |
See also: Trintellix side effects in more detail. |
See also: Wellbutrin XL side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Trintellix prices |
View all Wellbutrin XL prices |
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Dosage Form(s) Available | ||||||||||||||||||
N/A |
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Brand Names | ||||||||||||||||||
Rexulti |
N/A |
Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
91 hours |
66 hours |
30 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 580 drugs are known to interact with brexpiprazole:
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A total of 347 drugs are known to interact with Trintellix:
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A total of 497 drugs are known to interact with Wellbutrin XL:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
July 10, 2015 |
September 30, 2013 |
August 28, 2003 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.