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Esketamine User Reviews & Ratings (Page 5)

Brand names: Spravato

Esketamine has an average rating of 6.2 out of 10 from a total of 125 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 31% reported a negative experience.

Reviews for Esketamine

  • CatDa...
  • Taken for 1 to 6 months
  • December 19, 2022

For Major Depressive Disorder "So far, mixed emotions. I've done 6 weeks of biweekly treatment with esketamine which I felt were excellent results. Cut to 1 treatment per week and this week. It has been an amalgamation of depression and severe anger. Some of this change may have been brought about by stress due to my wife's rapidly disintegrating health and fear of her losing her other leg. She is an amputee, a cancer survivor with bilateral percutaneous nephrectomies, an Indiana pouch abdominal urinary bladder replacement), a colostomy, and end-stage renal disease. This week she suddenly developed pressure sores on her right foot almost identical to the one that cost her her left leg 9 months ago. Needless to say, I am extremely upset at the thought of her losing her right leg and praying the doctors can make it heal. When esketamine was working, prior to the events of this week, all was wonderful. I hope that comes back."

9 / 10
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2 Report
  • Lones...
  • May 7, 2021

For Depression "I've had several Spravato treatments. I must say they have helped me tremendously. All the blah blah blah from researchers who say not enough tests have been done but as I'm sure that while these researchers/MDs treat major depressive disorder, they themselves have not experienced MDD. Spravato has helped me immensely. No SSRI or SNRI has ever really helped. Those drugs, too, have been pushed by big Pharma. I've suffered from depression most of my life. This is the first medication where I have experienced dramatic improvement. Don't know what will happen after I've completed my treatments. But I'm grateful for the relief Spravato has given me."

10 / 10
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3 Report
  • James...
  • Taken for 1 to 6 months
  • September 6, 2021

For Major Depressive Disorder "I was on Spravato Nasal for about four to six months at the end of November 2019 insurance was cut off and I ended up in psych wards with major severe horrible psychosis and now we’re in September 2021 I am still having problems with hearing scary stuff, I felt/feel possessed I have psychic abilities/paranoia phobias? Intrusive voices, a lot of negative side effects, am I stuck in the K Hole? Has anyone else had horrific withdrawals and had it mess with your head? I thought I was crazy before haha, I’m scared."

1 / 10
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1 Report

Frequently asked questions

  • RedEyes
  • Taken for 1 to 6 months
  • March 11, 2023

For Depression "It cured my depression. I tried SSRI and tricyclic antidepressants with no benefits. Now I am feeling good thanks to Esketamine. It started to work in one month and I was 100% fine at the end of the second month. Now I m still doing my third month and I have no relapses at all. We are scaling up the drug until it is removed. I'm from Italy here is free thanks to the National Health Service."

10 / 10
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  • Kate
  • Taken for less than 1 month
  • June 16, 2022

For Depression "I tried 4 doses of high-dose esketamine. It was absolutely useless! Waste of time! Waste of money! The only effect I experienced was that it tasted bitter when it dripped down my throat. I did not have dissociations, hallucinations, nausea, drowsiness, dizziness or anything else. My vital signs also never changed at all. I simply got angry because I was forced to sit in empty room, bored silly for 2 hours each time. It did nothing for my depression, suicidal ideation or panic attacks. Giving me bad tasting saline would have the same effects as esketamine (and be much cheaper). I think it works purely on a placebo effect! I also haven't responded to numerous antidepressants, CBT or any other treatments either."

1 / 10
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Are you taking this medicine?

  • HOPEF...
  • Taken for 1 to 6 months
  • June 7, 2023

Spravato (esketamine) for Major Depressive Disorder "Although I haven't seen any results yet, it's important to remember that everyone's response can be different. After undergoing eight sessions, I haven't experienced any improvements. However, if you delve into the research, you'll find that this treatment was originally used as a horse tranquilizer. Logically, it seems plausible that a tranquilizer could be effective for addressing both anxiety and depression."

6 / 10
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0 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • December 27, 2019

Spravato (esketamine) for Depression "Depressed NO MORE.. Thanks Spravato"

10 / 10
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59 Report
  • Traci
  • Taken for 1 to 6 months
  • October 6, 2022

Spravato (esketamine) for Major Depressive Disorder "Spravato has done absolutely nothing for me. I’ve become worse than when I started and I didn’t think that was possible. I am trying very hard not to commit suicide"

1 / 10
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23 Report
  • bob
  • Taken for 1 to 6 months
  • November 4, 2023

Spravato (esketamine) for Major Depressive Disorder "Improvement in mood overall. Improvement in motivation. It has been very helpful. Only downside is having to go to the doctor's office once a week for the 2-hour session."

10 / 10
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9 Report
  • Bruno
  • Taken for 1 to 6 months
  • January 24, 2020

Spravato (esketamine) for Depression "Really Helped. IV is better, but this bridges the gap"

10 / 10
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35 Report
  • 777993
  • October 15, 2019

Spravato (esketamine) for Depression "Anybody have increased suicidal thought on spravato?"

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35 Report
  • Santa...
  • Taken for 1 to 6 months
  • June 27, 2019

Spravato (esketamine) for Depression "I'm on Spravato and the 56 mg dose is too much. Sick for 4 days after. Then 1 or 2 ok days. Where are all the other reviews? Drs know all that I know. They are no help at all"

2 / 10
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34 Report
  • Still...
  • Taken for 1 to 6 months
  • September 24, 2019

Spravato (esketamine) for Depression "Have been on spravato for over a month now and developing headaches. My anxiety level is through the roof. Still sad but not crying. Going in for assessment tomorrow."

1 / 10
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32 Report
  • John...
  • Taken for 1 to 6 months
  • December 15, 2020

Spravato (esketamine) for Major Depressive Disorder "Once the sedative effects are no longer felt you go back to being able to suppress your thoughts that you don't want to think about. It worked until my body got used to it."

6 / 10
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25 Report
  • Tara
  • Taken for less than 1 month
  • March 9, 2021

Spravato (esketamine) for Major Depressive Disorder "My first time was yesterday and it was not a good experience. I want to ask if the 2nd time may be better?"

5 / 10
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18 Report
  • Shakes
  • Taken for 1 to 6 months
  • March 13, 2024

Spravato (esketamine) for Major Depressive Disorder "I have had a very positive experience so far. It's been a rough road, but I now have some hope. I pray that this treatment will be the end of the nightmare of MDD."

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2 Report
  • Fly...
  • Taken for 1 to 6 months
  • February 1, 2023

Spravato (esketamine) for Major Depressive Disorder "I have had 15 treatments and have not gotten any better. Don't know if it's worth continuing treatments, speaking with my DR today. 25+ years of Treatment Resistant depression, nothing yet."

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8 Report
  • Jules
  • Taken for less than 1 month
  • August 10, 2021

Spravato (esketamine) for Depression "Just had my first treatment. I shouldn’t have been anxious, it was a calm, relaxing experience."

9 / 10
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13 Report
  • Guy...
  • Taken for less than 1 month
  • November 12, 2021

Spravato (esketamine) for Depression "Works great, helps with depression and leaves me feeling wonderful."

10 / 10
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12 Report
  • TheSc...
  • Taken for 6 months to 1 year
  • July 24, 2022

Spravato (esketamine) for Major Depressive Disorder "It worked, but it was short term relief. I had to discontinue due to getting migraine headaches that got worse"

5 / 10
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8 Report
  • AlboK
  • Taken for 1 to 6 months
  • March 7, 2022

Spravato (esketamine) for Depression "8 treatments @28mgs, last two treatments felt terrible during and 3 days after can't sleep and feel sick. Went up to 54mgs sickly past 4 days can't sleep. This is horrible medicine."

1 / 10
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9 Report
  • Still...
  • Taken for 1 to 6 months
  • August 3, 2021

Spravato (esketamine) for Depression "Part of a clinical trial for treatment resistant depression without any other antidepressants. I have 2 treatments left and it hasn't worked at all and has made my accompanying anxiety worse!"

2 / 10
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10 Report
  • kuser
  • Taken for 6 months to 1 year
  • July 2, 2021

For Major Depressive Disorder with Acute Suicidal Ideation "It erases suicidal ideation. I still have severe depression but no more thoughts of wanting to end it."

8 / 10
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9 Report
  • Depre...
  • January 7, 2023

Spravato (esketamine) for Depression "Spravato worked when NOTHING else did. My doctor wanted to Rx another SSRI but I heard about Spravato as adjunctive tx"

10 / 10
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5 Report
  • Capti...
  • Taken for 6 months to 1 year
  • September 13, 2020

For Depression "I am now the poster child for this medication esketamine it absolutely saved my life! and it also helped with substance abuse which I've struggled with my entire life."

10 / 10
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10 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.