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EpiCeram User Reviews & Ratings

EpiCeram has an average rating of 7.9 out of 10 from a total of 30 reviews on Drugs.com. 79% of reviewers reported a positive experience, while 18% reported a negative experience.

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Dry Skin  
7.9
30 reviews for Dry Skin 520 medications
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Reviews for EpiCeram

  • Final...
  • Taken for 1 to 6 months
  • February 4, 2014

For Dry Skin "Have suffered from eczema all over face, neck, upper body. Nothing worked, and I had to moisturize every 15-30 mins throughout the day. 2 yrs ago, I stopped using topical steroids and had a serious rebound effect of worsening eczema. Since then, it's been manageable, but has never improved. I've tried changing my diet, going organic, different moisturizers, bleach baths, Bactroban, etc. It was hard to get the prescription as this is a product that not many Drs are familiar with. In 2 weeks, I almost finished the 90g tube, but my skin improved so much! My face is baby-smooth. I could go for 8 hrs without moisturizer! I finally have hope again. It still itches, but the skin quality has drastically improved. No side effects. And no more steroids!"

10 / 10
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66 Report
  • Anonymous
  • Taken for less than 1 month
  • February 14, 2013

For Dry Skin "My partner has suffered from severe facial eczema for the past few years, far worse than she had ever experienced before. We tried everything, from dietary interventions to Elidel to various steroids. We were truly growing quite desperate, as the eczema was so severe it was limiting my partner's ability to go out, work, or even smile and laugh. EpiCeram has completely turned her condition around, to the point where the facial eczema is almost totally eliminated. The results were FAR beyond what I even dared hope for."

10 / 10
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58 Report
  • rob...
  • August 9, 2010

For Dry Skin "I have suffered with atopic dermatitis (moderate-severe) for 10 years. The inflammation and itchiness has been non-stop. My skin has been red and inflamed on my face, neck, arms, hands, and most of my body. Often, my skin has become so damaged from itching and scratching that various regions of my skin have split, such as my eyelids, neck, and knuckles. I HAVE USED EPICERAM FOR 1 WEEK AND ALL THE REDNESS HAS NEARLY CLEARED UP AND THERE ARE NO SPLITS AT ALL. I FEEL GREAT!! I can sleep comfortably. I can shower without the pain of water stinging my damaged skin. I can exercise again without sweat causing burning. I highly recommend this cream."

9 / 10
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61 Report
  • Momof
  • Taken for 1 to 6 months
  • March 1, 2018

For Dry Skin "I have been stripping my skin w high end acids/RetinA/over-exfoliant for years. I was extremely dry and flaky. My skin started to react to any extreme temperature or touch. I stripped the barrier of my skin and it was always angry. My Derm gave me this for Dermatitis. It took a few weeks but all my issues have disappeared. I am afraid to use anything else. It isn’t greasy and at times I feel like I need more moisture. However, I resist adding anything more than this cream. I can’t find the reason why this is by Rx only though?!?!"

10 / 10
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32 Report
  • Doobug
  • Taken for less than 1 month
  • September 4, 2017

For Dry Skin "I have suffered from eczema - especially on and around my eyelids, and rosacea all over my face for about 5 years now. (Started when I was about 35). If I sit next to a fire, my face gets hot and breaks out, if I am out in the cold, my face breaks out. My skin was dry and flaky, and felt like my face was chapped all the time. I was having to apply moisturizer 5-6 times a day. It was awful! I've been using Epiceram for 2 weeks, and my skin has been completely transformed! My skin is super smooth and hydrated, my eczema is totally gone. My face is not breaking out from heat/cold! My pore size looks smaller. This stuff is amazing! I wish I could take a bath in it!"

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30 Report

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  • Anonymous
  • January 14, 2012

For Dry Skin "Epi-ceram cream is amazing for eczema! The same day I applied the cream I noticed and felt a difference within a few hours. Two days later the eczema on my eye lids and around my mouth were clear. I use the cream sparingly and it works better than ANY other prescription. My insurance didn't cover it but I'm so glad I took a chance and paid for it. It was well worth the $$. Hopefully it will soon be available over the counter!"

10 / 10
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46 Report
  • Rich...
  • July 29, 2020

For Dry Skin "I think I have found the holy grail. I have been an eczema sufferer my whole life. I recently finished a 6 year topical steroid withdrawal NIGHTMARE after using steroids for many years. At first it seemed as though my eczema had gone into remission, but after a few months I noticed problems with my skin again, more with dryness and flaking than active eczema I fought it for months with every alternative therapy, potion, oil, diet out there with no success. Out of desperation I visited the derm again who prescribed me Elidel, which IMO is just as bad as steroids. It was by chance I came upon an article about Epiceram. In a last ditch effort I had my derm prescribe it and decided to give it a try with 0 expectations. This is only the second day I've used it and it has completely changed my skin. I am in disbelief. I can't remember the last time my skin looked this smooth and normal. TO all those suffering with this hellish condition I urge you to give this a shot. Epiceram is a game changer"

9 / 10
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18 Report
  • Londo...
  • Taken for less than 1 month
  • April 4, 2017

For Dry Skin "I think some folks may be confused about what this is supposed to do and the days it takes to do it. It restores your skin's own barrier to help heal and prevent a "break" = eczema and atopic dermatitis. You put it on first, then your prescription a few minutes later, if you need one. You use it for at least 2-4 weeks to strengthen your own skin from the damaged outer layer so it stops and prevents an active break(out). Almost nothing worked on me, including "shielding lotions." From their instructions: Should EpiCeram® be prescribed along with corticosteroids or a topical immunomodulator, it is recommended to apply EpiCeram® just a few minutes before applying steroids or topical immunomodulator to allow proper penetration."

10 / 10
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25 Report
  • Tiger
  • July 24, 2019

For Dry Skin "My face had bright red almost raw patches of skin with no itching. Tried Aloe, Aveeno & everything made it worse. EpiCeram was like a miracle product & the only thing that cleared it up. However, after using for a while & rebuilding skin barrier I end up with dry flaky skin patches that then need mild exfoliation. I don’t know if this is from excess buildup of skin barrier or not. It’s become a vicious cycle. I’ve become my own advocate. In conclusion EpiCeram clears up rawness but then causes very dry flaky patches. I don’t find it moisturizing but it does help with raw skin"

8 / 10
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18 Report
  • proux...
  • November 30, 2010

For Dry Skin "I have moderate eczema around my eyelids, and though cortisone based creams do have a beneficial effect in bringing down the inflammation, irritation, scaling, dryness and itching, I was concerned that long term use would cause my skin to thin, and also that I might get glaucoma or cataracts. I decided to try Epiceram after reading that Stanford medical researchers now believe that eczema is not an autoimmune disorder, but is caused by a breakdown of the skin's natural barrier due to dryness. The theory is that if you can re-moisturize the skin, outside insults from the environment will not trigger an attack. After using it for 5 days, Epiceram worked amazingly well, but to avoid stinging in my eyes, I shut my eyes after applying to let it dry."

9 / 10
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35 Report
  • Khoupat
  • Taken for less than 1 month
  • April 14, 2015

For Dry Skin "I have been an eczema sufferer all of my life. For the most part I am eczema-free now except for my eyelids and intermittent body flares. I had been using Protopic which worked very well except I had a sensitivity to an inactive ingredient which caused large cysts on my eyebrow area which were painful. I was given trial samples of EpiCeram to use. Quite honestly, I do not find it helpful. The Protopic would clear my skin in 1-2 applications (along with the steroids for my body) whereas EpiCeram I would apply twice a day for an entire week and saw no improvement. In fact, I had a rash on my chest that I was applying the EpiCeram to and it seemed to make it worse.Used it on my face and broke out with small pimples and blotchy."

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24 Report
  • Skinb...
  • October 1, 2009

For Dry Skin "Cracked dry and itchy skin on my hands is much better after three weeks of use. I no longer fear getting my hands wet which used to cause a flare up of eczema especially on my knuckles. This is the best results I have had from any treatment in years. The only problem I did have was after putting it on my face after shaving (as directed by my doctor) vapors from the cream irritated my eyes."

9 / 10
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27 Report
  • Satis...
  • Taken for less than 1 month
  • October 2, 2015

For Dry Skin "Our baby girl had eczema and the normal oat bath & moisturizing routine was not helping. We had to see a Pediatric Dermatologist who prescribed EpiCream for regular use and Hydrocortisone cream for the more stubborn instances. We were honestly sceptical about using EpiCream and did not think this overpriced product will help, but nevertheless gave it a try. We were pleasantly surprised to find that the product worked very well for our baby and the eczema almost disappeared within 48 hours of usage. I have to agree with the reviewer earlier who mentioned that the cream creates more of a stinging sensation for the baby than a tingling sensation as mentioned by the manufacturers. Happy to be proven wrong in this instance."

10 / 10
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17 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 31, 2019

For Dry Skin "This stuff has been magical for my eczema and rashes on my hands! I've previously tried strong prescription steroid creams with no effect. I put this on a forming rash and it's gone within a couple of hours."

10 / 10
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10 Report
  • Cokes
  • February 27, 2020

For Dry Skin "Went to see my derm about a spot above my eyebrow and my hella dry skin and she knew right away that I have Basal Cell Carcinoma above my eyebrow and a rash all over my face that isn't dry skin. They did a biopsy of the cancer and then gave me a sample of this Epiceram for the rash/dry skin, I instantly fell in love with this medicine and then noticed on GoodRx how expensive it is. You can get it much cheaper through your derm so that's what I will have to do but this medicine has already made a serious difference in my skin in less than 12 hours."

10 / 10
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9 Report
  • Anonymous
  • May 21, 2010

For Dry Skin "My 4 month old baby boy has used this for a week and within 2 days of use, I noticed a big improvement in his skin. It had become soft again not so dry and rough. The only problem is he screams every time we put it on him so its more like stinging for the first 10 - 15 min, rather then tingling as listed in side effects."

8 / 10
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20 Report
  • JLLLL
  • October 1, 2017

For Dry Skin "I have been suffering pain/irritation/distraction where my eyeglasses touch my face for over a decade. Since I also have very severe dry eye syndrome, so my treatments have always focused on my eyes, out of desperation, I tried to treat my skin conditions instead since last year and tried different skin creams, including those with steroids, then came to Epiceram in May 2017. I have been using Epiceram since May, and my conditions have been improving every day, even though very slowly, understandably considering how bad and long my conditions are. I test my improvements by put my eyeglasses on and feel the level of pain and irritation under the nosepads, and Finally, yesterday, I began to wear glasses again...Amazing stuff"

9 / 10
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10 Report
  • Gailslp
  • Taken for 1 to 6 months
  • February 11, 2018

For Dry Skin "I have had outbreaks on the palms and between fingers over the past five years. It was painful and my skin would get quite raw at times. I tried over the counter creams and a cortisone cream prescribed by a dermatologist but nothing seemed to help. I started using the Epiceram cream prescribed by the same dermatologist and it took several days before I began to see results, but I can say that my hands are in better shape than they have been in years now. I am still cautious, using gloves when cleaning or washing dishes but I think that, although it has been a very slow, gradual process, there has been a significant improvement."

9 / 10
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9 Report
  • Archie
  • December 19, 2017

For Dry Skin "I have SEVERE contact dermatitis (CD) on my hands, and they had been dry - so dry that making a fist caused my fingers to split and bleed. CeraVe was suggested at first, but then I was prescribed Epiceram. The lotion worked well on the less severe areas, and I have had some healing after four weeks of use. However, my finger tips and two entire fingers have not improved at all. I believe this is because my condition is too severe for the lotion to do its job. For mild eczema or CD, I'm sure this will work - it does provide some relief. For me, however, it has not worked 100% - so it's getting a "middle of the road" rating."

6 / 10
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9 Report
  • Dee
  • Taken for less than 1 month
  • August 4, 2020

For Dry Skin "For six years I have battled lichen Planus on my ankles. Nothing worked. My doctor gave me some samples to try before purchasing. Epicerum has worked wonders. With the first dose, I felt some relief. No more itching. Sores have healed. After two weeks, my ankles are almost back to normal!"

10 / 10
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4 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 18, 2015

For Dry Skin "Does not work. Over the counter cortizone for eczema works better. This was an overpriced waste of money. Not only that, they have at the ready a list of nine reasons for not giving you the promised refund of any cost over $30. I got reason #6 which makes no sense, something about I filled the prescription within 25 days. Well...yes, of course, I did! What is your point?! In other words, you will not get a refund of any overage. Before paying the high price for this "product" try the popular cortisone brand from your neighborhood drug store for under ten dollars."

1 / 10
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7 Report
  • Sharon
  • Taken for less than 1 month
  • March 25, 2023

For Dry Skin "I asked my dermatologist for something for my extremely dry face. My face is so dry that it’s painful and my foundation is absorbed within minutes since my skin is looking for moisture. I do use a primer which does help. Epiceram made my skin even drier than it was and then I started breaking out at my jawline. At 70 years old I’m a little old for pimples. I’m going to try to use it for two weeks but if the rash gets worse I will stop and call the dermatologist."

1 / 10
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1 Report
  • gillian
  • Taken for 6 months to 1 year
  • April 7, 2023

For Dry Skin "This stuff has been a miracle for me! It really helps to heal severe dry skin from eczema and skin barrier damage. It also helps to heal cracks in the skin from dryness. No other over the counter cream has ever worked for me. This stuff really works at healing your skin!"

10 / 10
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  • Cynders
  • Taken for 1 to 6 months
  • March 19, 2024

For Dry Skin "I've been bothered by redness and extreme sensitivity on my neck for the past few years, which seemed to get worse after I developed rosacea on my chest. Even OTC products and moisturizers for "sensitive skin" didn't seem to help -- and my dermatologist said it was because my skin barrier was compromised and needed repair. My dermatologist prescribed EpiCream cream, and within three or four days, the redness and irritation on my neck improved quickly. It still flares up easily, but I see improvement daily, including fewer wrinkles on my neck -- a bonus. The cream is soothing and a pleasure to use. I'd give it a 10 if it weren't so expensive."

9 / 10
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  • Denise
  • Taken for 1 to 2 years
  • July 1, 2023

For Dry Skin "Epiceram was the only lotion that worked for my troubled skin. I was breaking out on my hands, arms, neck, ears, and head. After finding Epiceram, I had relief. Before finding Epiceram, I was not sleeping well as I would wake up with itchy, burning skin that became blistered and hot. After changing my diet along with using Epiceram, I now haven't lost one night of sleep. I carry Epiceram in my purse and can apply it whenever my skin starts breaking out."

10 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.