Neumega

Generic Name: oprelvekin (oh-PREL-ve-kin)
Brand Name: Neumega

Neumega may cause allergic reactions, including severe allergic reactions. Do not use any more of Neumega and seek immediate medical help if you develop symptoms of an allergic reaction, such as rash; hives; itching; trouble breathing; tightness in your chest; or swelling of the mouth, face, lips, or tongue.


Neumega is used for:

Prevention of severe reductions in the number of blood clotting cells (platelets) caused by some chemotherapy. It may also be used for other conditions as determined by your doctor.

Neumega is an interleukin. It works by stimulating certain body chemicals to produce platelets that function normally and have a normal life span.

Do NOT use Neumega if:

  • you are allergic to any ingredient in Neumega

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Neumega:

Some medical conditions may interact with Neumega. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of leukemia, multiple myeloma (disease of the bone marrow), bone marrow transplant, brain tumors, or other tumors involving the central nervous system
  • if you consume 3 or more alcohol-containing beverages a day
  • if you have a history of irregular heart rhythm, high blood pressure, stroke, congestive heart failure, other heart disease, or lung problems
  • if you have kidney problems, are taking diuretics ("water pills") to decrease the amount of fluid in your body, have a history of fluid retention, or have low potassium levels in your blood
  • if you have a history of swelling of the eye or have an eye disease (eg, papilledema)

Some MEDICINES MAY INTERACT with Neumega. However, no specific interactions with Neumega are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Neumega may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Neumega:

Use Neumega as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Neumega comes with an additional patient leaflet. Read it carefully and reread it each time you get Neumega refilled.
  • Neumega is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using Neumega at home, carefully follow the injection procedures taught to you by your health care provider.
  • If Neumega contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Neumega should be injected in the stomach, hip, or thigh. It may be injected into the upper arm if it is given by another qualified individual. Neumega must be injected under the skin not in the muscle.
  • When drawing a dose into a syringe, be sure to follow the procedure demonstrated to you to prevent contamination of the vial, syringe, or medicine. Never touch the rubber stopper of the vial or needle of the syringe with your fingers.
  • Carefully check that you have drawn the correct dose before administration.
  • Do not shake Neumega.
  • Neumega works best if it is taken at the same time each day.
  • Continue using Neumega for the full course of treatment even if you feel better in a few days.
  • You should stop using Neumega at least 2 days before starting the next planned cycle of cancer chemotherapy.
  • Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Neumega, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. If more than one dose is missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Neumega.

Important safety information:

  • Neumega may cause dizziness or fainting. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Neumega. Using Neumega alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Serious eye problems (papilledema) may occur more often in children.
  • Contact your health care provider if shortness of breath or irregular heartbeat occurs or worsens while using Neumega.
  • LAB TESTS, including complete blood cell count, platelet count, and electrolyte levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Neumega with extreme caution in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Neumega during pregnancy. It is unknown if Neumega is excreted in breast milk. Do not breast-feed while taking Neumega.

Possible side effects of Neumega:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Chills; constipation; cough; diarrhea; dizziness; fever; flushing; hair loss; headache; increased cough; indigestion; inflammation or sores of the mouth or lips; joint pain; loss of appetite; mild swelling of the arms and legs; muscle pain; nausea; nervousness; pain; runny nose; shortness of breath when moving; sleeplessness; sore throat; stomach pain; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); eye infection; eye pain; fainting; heart flutter; irregular or fast heartbeat; pain, redness, or swelling at the injection site; pounding in the chest; severe headache, dizziness, or one-sided weakness; unusual bruising; unusual or severe swelling; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include continuing irregular or fast heartbeat.

Proper storage of Neumega:

Store powder and the dilution solution in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Protect from light. Do not freeze. Mixed solution must be used within 3 hours and be stored in the vial at 36 to 46 degrees F (2 and 8 degrees C) or at room temperature, up to 77 degrees F (25 degrees C). Do not freeze or shake Neumega after it is mixed. Do not store in the bathroom. Keep Neumega out of the reach of children and away from pets.

General information:

  • If you have any questions about Neumega, please talk with your doctor, pharmacist, or other health care provider.
  • Neumega is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Neumega or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Neumega. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Neumega. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Neumega.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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